Rewind aging at the source.
High potency Utheverยฎ NMN: the full 1,000 mg dose used in the studies, 99+% pure.
- Powers longevity, repairs DNA and restores energy
- 7 patents, one double-blind, placebo-controlled human trial
- Most people feel a difference in energy within the first two weeks
30-days to get a FULL refund on prepaid 12-month subscriptions
See the results in your bloodwork or don't pay
FREE SHIPPING IN THE US
More than double the NMN of 4 out of the 5 top-selling competitors tested. See every result
Label says 1,000 mgTested 1,139.6 mg
Current batch · Lot N26231005 Download (PDF)
SEE THE RESULTS IN YOUR BLOODWORK OR DON'T PAY
Take NMN-99 for 4 months, with a blood test at the beginning and blood test at the end. If you don't see an improvement in biomarkers, tell us and you'll get a full refund.
Full refund within 180 days for any reason. (For prepaid annual subscriptions, due to deep discount, full refund only within 30 days of receiving first shipment.)
- Test before you start
- Every day for 4 months
- Test again at 4 months
- Before you start
Run an NAD+ blood test, so you have your own number to compare.
- First two weeks
NMN-99 starts rebuilding your NAD+, and most people feel a difference in energy.
- Month after month
Your NAD+ stays up and keeps DNA repair running. You won't feel this part, which is why the NAD+ test matters.
- 4 months and beyond
While you're still taking it, run the same NAD+ test again at the same lab, and compare.
2 capsules daily, with or without food. Up to two servings a day.
NMN-99
The blood tests for NMN-99
Get these before you start, then again after 4 months, while you're still taking it. Your doctor can order the blood work, and the NAD+ test is a finger-prick kit you order online and do at home.
- NAD+ blood test: higher is better.An at-home finger-prick kit.
- ALT: lower is better.A liver marker. It's on the standard metabolic panel (CMP).
- Fasting glucose and fasting insulin: lower is better.How well your body handles sugar.
- Total cholesterol: lower is better.All the cholesterol in your blood, in one number.
- LDL cholesterol: lower is better.The "bad" cholesterol. It builds up in your arteries.
NAD+ is the big one. It's what NMN raises, and yours has been falling since you were 25. Use the same NAD+ lab both times, so the numbers line up.
If your numbers haven't improved after 4 months, just email hello@opus.life, and we'll refund everything you paid.
Full refund within 180 days for any reason. (For prepaid annual subscriptions, due to deep discount, full refund only within 30 days of receiving first shipment.)
This is how you age.
Your DNA gets damaged every day, and unless the damage is repaired it directly accelerates aging. That repair runs on NAD+. But the NAD+ your body makes drops year after year, so the damage keeps coming while the fuel to fix it runs down.
Every cell runs on one molecule: NAD+.
Your NAD+ begins to drop around 25. It's 25% gone by your mid-30s, and 50% gone by 50. Everything that runs on NAD+ slows down with it, including the enzymes that repair your DNA.
NMN is how you get it back. Your body makes NMN for one purpose, to rebuild NAD+, so what you take converts in a single step and goes straight to work.
Get more NAD+ today.
Daily NMN more than DOUBLES NAD+ levels
What higher NAD+ does for you
Longevity
NAD+ fuels the sirtuins, the enzymes science links most directly to a longer life. When NAD+ drops, the sirtuins shut down. Raise it and they go back to work.
DNA repair
Your DNA takes tens of thousands of breaks every day. NAD+ powers the enzymes that repair them. Without enough of it the damage stops being repaired and starts compounding, and that compounding is what aging looks like from the inside.
Energy
NAD+ is how your mitochondria generate ATP, the energy every cell runs on. It also powers autophagy, the system your cells use to clear out worn machinery and rebuild from within, so the mitochondria that stop working get recycled instead of accumulating.
(Igarashi et al., 2022; Yoshino et al., 2021; Morifuji et al., 2024)
Brain
Your neurons are among the hungriest cells you have, and brain NAD+ declines significantly with age. NAD+ fuels both their energy and their repair pathways.
Heart
NAD+ drives energy metabolism and vascular function across your cardiovascular system.
(Zhang et al., 2026; Yi et al., 2023; Katayoshi et al., 2023)
Skin
NAD+ supports the cells that build collagen and elastin. When it drops, skin loses its ability to repair and renew, and that is visible long before anything else is.
Independent lab tests
More than double the NMN of 4 out of the 5 top-selling competitors tested.
We bought the 5 top-selling NMN supplements online and had them shipped directly to an independent 3rd-party lab. The lab tested each one the same way as NMN-99, and you can download every report.
| Product | Tested |
|---|---|
 |
1,139.6 mgLab report |
| Black Forest NMN 1000 mgLabel says 1,000 mg | 905.0 mgLab report |
| Renue By Science Liposomal NMNLabel says 500 mg | 481.0 mgLab report |
| partiQlar Pure NMN 500 mgLabel says 500 mg | 466.8 mgLab report |
| Nutricost NMN 500 mgLabel says 500 mg | 455.1 mgLab report |
| Genex Formulas NMN 250 mgLabel says 250 mg | 260.7 mgLab report |
In a separate test of NMN supplements, 14 out of 22 contained less than 1% of the NMN on the label (Niagen Bioscience, 2021).
You can go back to 25.
Taking NMN has been shown to more than double NAD+ levels, restoring NAD+ to the level it was at age 25. (This applies on average and not to every individual.)
Igarashi M, et al. npj Aging. 2022;8(1):5. Yi L, et al. GeroScience. 2023;45(1):29-43.
Your NMN has a name.
NMN-99 is made with Utheverยฎ, the worldโs first patented NMN backed by its own randomized, double-blind, placebo-controlled human trial. 7 patents. One ingredient. Verified at 99+% purity in the beta form your body can actually use.
Beyond the certificate of analysis, an independent 3rd-party lab tests every batch, and its report for the batch on sale now is on this page.
Made right, in California.
Every ingredient and every milligram on the Supplement Facts panel.
Supplement Facts
Serving Size: 2 Capsules
Servings per container: 30
| Amount per serving | %DV | |
|---|---|---|
| Utheverยฎ NMN (ฮฒ-Nicotinamide Mononucleotide) | 1000mg | ** |
** Daily Value Not Established
NMN-99 is produced in California, in a highly advanced FDA registered facility with GMP certification from NSF, UL and the Natural Products Association, as well as organic and Non-GMO certifications. Independently lab tested for purity and potency.
Made without Milk, Eggs, Nuts, Crustaceans, Shellfish, Wheat, Soy and Sesame.
Everything else on the label
What makes NMN-99 second to none?
NMN only delivers on its promise when it is the real thing: the bioactive ฮฒ-form, verified pure, and dosed high enough to meaningfully raise your NAD+.
Yet more than half of the NMN supplements sold today deliver 500mg or less, much of it generic bulk powder with little independent proof of its purity or its active content.
NMN-99 uses only Utheverยฎ, the world's first clinically-proven branded NMN, verified at 99%+ purity in the ฮฒ-form your body can actually use.
Every serving delivers a full 1000mg, the daily dose recommended by leading longevity experts. Some go as high as twice that, so NMN-99 is built to be taken once or twice a day.
7 patents 1 ingredientโ
1000mg 99+% PURE NMN per serving
Other ingredients: naturally derived plant-based hypromellose capsules, organic acacia fiber, organic Nu-Flowยฎ rice hulls,
MANUFACTURED FOR Opus Longevity, Inc โข San Francisco, CA 94104 โข www.opus.life
Suggested use: Take 2 capsules daily, with or without food. May increase to twice daily. For best results, take for a minimum of 4 months and beyond.
Consult a medical doctor before taking this or any other supplement if you are pregnant, nursing, have a medical condition or are taking any medications.
Utheverยฎ is a trademark of Effepharm Ltd.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Keep this and all other supplements out of the reach of children.
NMN-99 pairs with BROQ and SPMD-99.
SPMD-99 switches on autophagy, your cells' cleanup, and NMN-99 supplies the NAD+ that powers it.
BROQ supports a longer, healthier life and supercharges your immune system. Spermidine is linked to nearly 6 years of longer life, and SPMD-99 supports fuller hair and a stronger heart.
Both go into your cart as separate items, on the plan shown on the button.
Add bothSubscribe & Save ยท $102.00/moLeading longevity scientists recommend sulforaphane, NMN and spermidine more than any other supplements.
The questions people ask.
Do I need to take it with food?
No. Take two capsules in the morning, with or without food. You can take up to two servings (4 capsules) a day.
Why this one over cheaper NMN?
Because in this category, cheap usually means you're not getting the molecule you paid for. In a test of 22 NMN supplements, 14 contained less than 1% of the NMN on the label (Niagen Bioscience, 2021). NMN-99 uses only Utheverยฎ, the world's first patented NMN, backed by its own randomized, double-blind, placebo-controlled human trial.
What's in it, and how do I know?
Three ingredients, in plant-based capsules: Utheverยฎ NMN, organic acacia fiber and organic rice hulls. That's the whole list. We buy each product online and have it shipped directly to an independent 3rd-party lab. Lab reports state that product was received in unopened retail packaging. Every batch is tested, and we publish the report. The batch on sale now measured 1,139.6 mg per serving, against 1,000 mg on the label.
Why 1,000 mg?
It's the dose used in the studies. In a controlled trial, NMN at this level raised blood NAD+ 3.7 times above placebo (Bhasin et al., 2023), and a separate trial found higher doses produced the greatest gains in aerobic capacity (Liao et al., 2021). That's why you can take NMN-99 once or twice a day.
How soon will I feel a difference?
Most people feel a difference in energy within the first two weeks. NAD+ powers every cell in your body, and its work on DNA repair and aging builds quietly over months, so stay with it for at least 4 months. Run an NAD+ blood test before you start and again at 4 months, while you're still taking it. Use the same lab both times, and compare the numbers.
What if it's not for me?
30-days to get a FULL refund on prepaid 12-month subscriptions
It's on us, even on a one-time purchase. Just email hello@opus.life with your order number, and you get a refund.
Can I pause or cancel?
With Subscribe & Save, yes, any time, and you do it yourself. Log in to your account to pause, skip a delivery, change the date or cancel outright. You can also email hello@opus.life and we'll take care of it. The Annual Subscription is prepaid for 12 months. How subscriptions work
Can I take NMN-99 with BROQ and SPMD-99?
Yes. They're best as a stack. Take NMN-99 and BROQ in the morning, and SPMD-99 with your last meal. That said, any time of day works. Consistency matters most.
The new Gold Standard of NMN supplements
Made with Utheverยฎ NMN: the first clinically proven NMN in the world. Full 1000mg dosage used in studies. 99+% pure.
30-days to get a FULL refund on prepaid 12-month subscriptions
FREE SHIPPING IN THE US